Disease emergence and resurgence threatens the sustainability of healthy population levels and long-term survival for many wildlife species in the Northeast. Disease outbreaks in wildlife can erode biodiversity and threaten ecosystem health. This symposium brings together university researchers and state agency staff to present their findings on diseases that are significant to wildlife conservation, as well as diseases that are transmitted between wildlife and domestic animals. Symposium speakers will provide information on a diverse array of topics pertaining to wildlife health, including: the recent epizootics of Hemorrhagic Disease (HD) in white-tailed deer (Odocoileus virginianus), emerging diseases of amphibians, lead in Bald Eagles (Haliaeetus leucocephalus), factors affecting moose health in New York, mange in black bears (Ursus americanus), mass mortality of Common Eiders (Somateria mollissima), canine distemper in fisher (Pekania pennant) populations, and threats to Canada Lynx (Lynx canadensis) health. Through this symposium, we seek to raise the profile of wildlife disease research and management in the region.